A membrane-targeted photoswitch restores physiological ON/OFF responses to light in the degenerate retina
Abstract The lack of effective therapies for visual restoration in Retinitis pigmentosa and macular degeneration has led to the development of new strategies, such as optogenetics and retinal prostheses.However, visual restoration is poor due to the massive light-evoked activation of retinal neurons, regardless of the segregation of visual informat